Structure of PDB 8oeq Chain D

Receptor sequence

>8oeqD (length=214) Species: 5476 (Candida albicans) [Search protein sequence]

VVDPFTRKDWFDIKAPTTFENRNVGKTLINRSTGLKNAADGLKGRVFEVC
LADLQGSEDHSYRKIKLRVDEVQGKNLLTNFHGLDFTSDKLRSLVRKWQS
LVEANVTVKTSDDYVLRVFAIAFTKRQPNQIKKTTYAQSSKLREVRKKMI
EIMQREVSNCTLAQLTSKLIPEVIGREIEKSTQTIFPLQNVHIRKVKLLK
QPKFDLGSLLALHG

3D structure

PDB

8oeq Drug-induced rotational movement of the ribosome is a key factor for read-through enhancement

Chain

Resolution

3.3 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	D	P23 K27 R111 V114 R115 K116 W117 Q118 L120 E122 N124 R136 F138 Q146 P147 N148 Q149 I150 K151 Y155 Q157 S158 S159 K160 R165 Q202 T203 I204 F205 P206 K214 K216	P4 K8 R92 V95 R96 K97 W98 Q99 L101 E103 N105 R117 F119 Q127 P128 N129 Q130 I131 K132 Y136 Q138 S139 S140 K141 R146 Q183 T184 I185 F186 P187 K195 K197
BS02	PAR	D	D104 S107 L110 R111 R213 K214	D85 S88 L91 R92 R194 K195

External links

PDB	RCSB:8oeq, PDBe:8oeq, PDBj:8oeq
PDBsum	8oeq
PubMed
UniProt	A0A8H6C387

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