Structure of PDB 8jy6 Chain D

Receptor sequence
>8jy6D (length=242) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
YRDYVAEFLGNFVLIYIAKGAVITSLLVPDFGLLGLTIGIGVAVTMALYV
SLGISGGHLNSAVTVGNAVFGDFPWRKVPGYIAAQMLGTFLGAACAYGVF
ADLLKAHGGGELIAFGEKGIAWVFAMYPAEGNGIFYPIFAELISTAVLLL
CVCGIFDPNNSPAKGYETVAIGALVFVMVNNFGLASPLAMNPSLDFGPRV
FGAILLGGEVFSHANYYFWVPLVVPFFGAILGLFLYKYFLPH
3D structure
PDB8jy6 Structural insights into drug transport by an aquaglyceroporin.
ChainD
Resolution2.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 L1U D H128 L129 M196 I241 V245 A259 N261 L264 H58 L59 M126 I171 V175 A189 N191 L194
Gene Ontology
Molecular Function
GO:0015204 urea transmembrane transporter activity
GO:0015250 water channel activity
GO:0015254 glycerol channel activity
Biological Process
GO:0006833 water transport
GO:0015791 polyol transmembrane transport
GO:0015793 glycerol transmembrane transport
GO:0071918 urea transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8jy6, PDBe:8jy6, PDBj:8jy6
PDBsum8jy6
PubMed38734677
UniProtQ6ZXT3|AQP2_TRYBB Aquaglyceroporin-2 (Gene Name=AQP2)

[Back to BioLiP]