Structure of PDB 8juw Chain D

Receptor sequence
>8juwD (length=530) Species: 9606 (Homo sapiens) [Search protein sequence]
LDSSVRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGP
PGTGKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFD
QAYQMRPSIIFFDQIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDSRGEI
VVIGATNRLDSIDPALRRPGRFDREFLFSLPDKEARKEILKIHTRDWNPK
PLDTFLEELAENCVGYCGADIKSICAEAALCALRRRYPQIYTTSEKLQLD
LSSINISAKDFEVAMQKMIPASQRAVTSPGQALSTVVKPLLQNTVDKILE
ALQRVFPHAEYQPMSFRPRILIVGEPGFGQGSHLAPAVIHALEKFTVYTL
DIPVLFGVSTTSPEETCAQVIREAKRTAPSIVYVPHIHVWWEIVGPTLKA
TFTTLLQNIPSFAPVLLLATSDKPHSALPEEVQELFIRDYGEIFNVQLPD
KEERTKFFEDLILKQAAKPPHERLKNLLKTVVKKSQNYNIFQLENLYAVI
SQCIYRHRKDHDKTSLIQKMEQEVENFSCS
3D structure
PDB8juw Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication.
ChainD
Resolution3.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP D P469 G470 T471 G472 K473 T474 L475 N575 H611 P51 G52 T53 G54 K55 T56 L57 N157 H193
BS02 ATP D R586 R589 R168 R171
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:8juw, PDBe:8juw, PDBj:8juw
PDBsum8juw
PubMed37770645
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

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