Structure of PDB 8jko Chain D

Receptor sequence
>8jkoD (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
GKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQYNREEDAALFK
AWALFKGKFREGIDKPDPPTWKRRLRCALNKSNDFEELVERSQLDISDPY
KVYRIVPE
3D structure
PDB8jko Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
ChainD
Resolution2.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D W54 H56 A57 K59 K94 R95 R98 K103 W33 H35 A36 K38 K72 R73 R76 K81
BS02 dna D G22 L24 H56 G58 K59 W74 K78 R96 K103 G1 L3 H35 G37 K38 W52 K56 R74 K81
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8jko, PDBe:8jko, PDBj:8jko
PDBsum8jko
PubMed37683642
UniProtF2Z3D5

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