Structure of PDB 8jkn Chain D

Receptor sequence
>8jknD (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
GKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQNREEDAALFKA
WALFKGKFREGIDKPDPPTWKRRLRCALNKSNDFEELVERSQLDISDPYK
VYRIVPE
3D structure
PDB8jkn Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
ChainD
Resolution2.92 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D W54 H56 K59 K94 R98 N102 K103 W33 H35 K38 K71 R75 N79 K80
BS02 dna D G22 L24 H56 K59 W74 K78 K80 R96 K103 G1 L3 H35 K38 W51 K55 K57 R73 K80
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8jkn, PDBe:8jkn, PDBj:8jkn
PDBsum8jkn
PubMed37683642
UniProtF2Z3D5

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