Structure of PDB 8jkl Chain D

Receptor sequence
>8jklD (length=108) Species: 9606 (Homo sapiens) [Search protein sequence]
KLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAALFK
AWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISDPY
KVYRIVPE
3D structure
PDB8jkl Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
ChainD
Resolution2.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D W54 H56 A57 K59 Y62 K94 R98 K103 W32 H34 A35 K37 Y40 K72 R76 K81
BS02 dna D K23 L24 H56 G58 R64 W74 K78 K80 R96 A100 K103 K1 L2 H34 G36 R42 W52 K56 K58 R74 A78 K81
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8jkl, PDBe:8jkl, PDBj:8jkl
PDBsum8jkl
PubMed37683642
UniProtF2Z3D5

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