Structure of PDB 8jfm Chain D

Receptor sequence
>8jfmD (length=268) Species: 210 (Helicobacter pylori) [Search protein sequence]
MGFLKGKKGLIVGVANNKSIAYGIAQSCFNQGATLAFTYLNESLEKRVRP
IAQELNSPYVYELDVSKEEHFKPLYDSVKKDLGSLDFIVHSVAFAPKEAL
EGSLLETSKSAFNTAMEISVYSLIELTNTLKPLLNNGASVLTLSYLGSTK
YMAHYNVMGLAKAALESAVRYLAVDLGKHNIRVNALSAGPIRTLASSGIA
DFRMILKWNEINAPLRKNVSLEEVGNAGMYLLSSLSSGVSGEVHFVDAGY
HVMGMGAVEEATLLWDLH
3D structure
PDB8jfm The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis.
ChainD
Resolution2.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.1.9: enoyl-[acyl-carrier-protein] reductase (NADH).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD D G13 V14 A15 S19 I20 L40 D64 V65 S91 V92 A93 L143 S144 Y145 K162 A188 P190 I191 T193 A195 G13 V14 A15 S19 I20 L40 D64 V65 S91 V92 A93 L143 S144 Y145 K162 A188 P190 I191 T193 A195
Gene Ontology
Molecular Function
GO:0004318 enoyl-[acyl-carrier-protein] reductase (NADH) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006633 fatty acid biosynthetic process

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:8jfm, PDBe:8jfm, PDBj:8jfm
PDBsum8jfm
PubMed37779101
UniProtA0A086RSH0

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