Structure of PDB 8j6h Chain D

Receptor sequence
>8j6hD (length=407) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
RYRVEYHLKSHRKDEFIDWVKGLLASPFVLHAVSHEGDYNDDLATTQRVR
SQYADIFKDIEGLIKDKIEFDSRNLGQSRLNLLVPSIGTFFTELPLEQAF
LWEDSQRAISARRMVAPSFNDIRHILNTAQIFHFKKQENLHNGKVLRLVT
FDGDTNPVIPYILKLLRCGINVGIVTAAGYDEAGTYENRLKGLIVALHDS
TDIPVSQKQNLTIMGGESSYLFRYYEDPEEDNFGFRQIDKEEWLLPRMKA
WSLEDVEKTLDFAERTLNRLRKRLNLPSEISIIRKVRAVGIVPGERVKLD
REQLEEIVLTLQNTLESFAPSRRIQFSCFDGGSDVWCDIGGKDLGVRSLQ
QFYNPESPIQPSETLHVGDQFAPVGSANDFKARLAGCTLWIASPQETVNY
LHRLLET
3D structure
PDB8j6h Structure, cooperativity and inhibition of the inosine 5'-monophosphate-specific phosphatase from Saccharomyces cerevisiae.
ChainD
Resolution2.44074 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.99: IMP-specific 5'-nucleotidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NOS D D17 F19 G108 T109 F110 L114 L146 Q150 R425 T430 D14 F16 G88 T89 F90 L94 L126 Q130 R383 T388
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0050483 IMP 5'-nucleotidase activity
Biological Process
GO:0006190 inosine salvage
GO:0009117 nucleotide metabolic process
GO:0071590 nicotinamide riboside biosynthetic process
GO:0071592 nicotinic acid riboside biosynthetic process
Cellular Component
GO:0005575 cellular_component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8j6h, PDBe:8j6h, PDBj:8j6h
PDBsum8j6h
PubMed38362806
UniProtQ99312|ISN1_YEAST IMP-specific 5'-nucleotidase 1 (Gene Name=ISN1)

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