Structure of PDB 8j5t Chain D

Receptor sequence

>8j5tD (length=608) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]

SPLLEVTDLAVTFRTDGDPVTAVRGISYRVEPGEVVAMVGESGSGKSAAA
MAVVGLLPEYAQVRGSVRLQGTELLGLADNAMSRFRGKAIGTVFQDPMSA
LTPVYTVGDQIAEAIEVHQPRVGKKAARRRAVELLDLVGISQPQRRSRAF
PHELSGGERQRVVIAIAIANDPDLLICDDPTTALDVTVQAQILDVLKAAR
DVTGAGVLIITHDLGVVAEFADRALVMYAGRVVESAGVNDLYRDRRMPYT
VGLLGSVPRLDAAQGTRLVPIPGAPPSLAGLAPGCPFAPRCPLVIDECLT
AEPELLDVATDHRAACIRTELVTGRSAADIYRVKTEARPAALGDASVVVR
VRHLVKTYRLAKGVVLRRAIGEVRAVDGISLELRQGRTLGIVGESGSGKS
TTLHEILELAAPQSGSIEVLGTDVATLGTAERRSLRRDIQVVFQDPVASL
DPRLPVFDLIAEPLQANGFGKNETHARVAELLDIVGLRHGDASRYPAEFS
GGQKQRIGIARALALQPKILALDDPVSALDVSIQAGIINLLLDLQEQFGL
SYLFVSHDLSVVKHLAHQVAVMLAGTVVEQGDSEEVFGNPKHEYTRRLLG
AVPQPDPA

3D structure

PDB

8j5t An oligopeptide permease, OppABCD, requires an iron-sulfur cluster domain for functionality

Chain

Resolution

2.98 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	ATP	D	R147 E154 S156 G158 E159 Y359 S396 G397 S398 G399 K400 S401 T402 Q445 H558	R146 E153 S155 G157 E158 Y358 S395 G396 S397 G398 K399 S400 T401 Q444 H557
BS02	MG	D	S401 Q445	S400 Q444
BS03	ATP	D	F14 S43 G44 G46 K47 S48 A49 Q96 H213 R495 E499 S501 G503	F13 S42 G43 G45 K46 S47 A48 Q95 H212 R494 E498 S500 G502
BS04	MG	D	S48 Q96	S47 Q95
BS05	SF4	D	P249 C286 A289 C292 C299 C317 R319	P248 C285 A288 C291 C298 C316 R318

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0005524	ATP binding
GO:0016887	ATP hydrolysis activity
GO:0022857	transmembrane transporter activity

	Biological Process
GO:0015833	peptide transport
GO:0055085	transmembrane transport

	Cellular Component
GO:0005886	plasma membrane
GO:0009274	peptidoglycan-based cell wall

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Molecular Function

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Cellular Component

External links

PDB	RCSB:8j5t, PDBe:8j5t, PDBj:8j5t
PDBsum	8j5t
PubMed	38548954
UniProt	P9WQJ5\|Y1281_MYCTU Uncharacterized ABC transporter ATP-binding protein Rv1281c (Gene Name=Rv1281c)

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