Structure of PDB 8ipt Chain D

Receptor sequence
>8iptD (length=573) Species: 562 (Escherichia coli) [Search protein sequence]
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAG
VAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTF
SKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMV
VTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYR
QQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAI
MLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGA
FQHLGQVIASAVRITDLTDQKPEVTFPDTQTRVADRVSLTLRDVQFTYPE
QSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDPQQGEILLN
DSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALSEIL
RRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDQ
PTEGLDATTESQILELLAEMMREKTVLMVTHRLRGLSRFQQIIVMDNGQI
IEQGTHAELLARQGRYYQFKQGL
3D structure
PDB8ipt Cryo-EM structures of a prokaryotic heme transporter CydDC.
ChainD
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP D Y348 T375 G376 C377 G378 K379 S380 T381 Y348 T375 G376 C377 G378 K379 S380 T381
BS02 ATP D R473 G477 E479 R473 G477 E479
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0015439 ABC-type heme transporter activity
GO:0016887 ATP hydrolysis activity
GO:0042626 ATPase-coupled transmembrane transporter activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0006865 amino acid transport
GO:0033228 cysteine export across plasma membrane
GO:0034775 glutathione transmembrane transport
GO:0035351 heme transmembrane transport
GO:0045454 cell redox homeostasis
GO:0055085 transmembrane transport
GO:1903605 cytochrome biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055051 ATP-binding cassette (ABC) transporter complex, integrated substrate binding

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ipt, PDBe:8ipt, PDBj:8ipt
PDBsum8ipt
PubMed37144855
UniProtP23886|CYDC_ECOLI Glutathione/L-cysteine transport system ATP-binding/permease protein CydC (Gene Name=cydC)

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