Structure of PDB 8i24 Chain D

Receptor sequence
>8i24D (length=1152) Species: 637887 (Acetivibrio thermocellus DSM 1313) [Search protein sequence]
NNFDSIRIGLASPEKIREWSRGEVKKPETINYRTLKPERDGLFCERIFGP
QKDWECHCGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVSHI
WYFKGIPSRMGLLLDMSPRALEKILYFAAYVVIDPGQTPLSKKQILSEKE
YRDSLEKFGPKFRAGMGAEAVRELLQEINLDELSAELREEIKQSTGQKRV
RAIKRLEVVEAFRQSQNKPEWMILDVIPVIPPELRPMVQLDGGRFATSDL
NDLYRRVINRNNRLKRLLDLGAPDIIVRNEKRMLQEAVDALIDNGRRGRP
VTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKIYQ
CGLPKEMALELFKPFVMKKLVNDGLAHNIKSAKRMVERVRNEVWDVLEEV
IKEHPVLLNRAPTLHRLGIQAFEPVLVEGRALKLHPLVCTAYNADFDGDQ
MAIHVPLSAEAQAEARFLMLSANNLLKPQDGKPVAVPTQDMVLGSYYLTI
LKEGAKGEGRVFTSMDEAVMAYDNGEIELHSKIKVRMKRVVDGVEKSKII
ETTLGRLIFNEAIPQDLGFVDRSDPDKIFDLEVDFLVGKNELKKIIDKSI
KVHGTTKTAILLDKIKELGFKYSTKGAITISISDMVIPEVKAKYIKETEE
KIEKITKQYKRGLISDEERYNSVIAAWTEASENITRALINNLDRFNPVYM
MSQSGARGNINQIKQLAGMRGLMADTSGKTIEFPIKANFREGLTVMEFFI
STHGARKGLADTALRTADSGYLTRRLVDVSQDVIVRETDCGTRKGIEVTD
IKDGNEVIEELSERIIGRYPVGNIVHPETGEIIVEAGRMITDQDAEKIVK
AGIKKVRIRSVLTCHSEYGVCAKCYGANLATGEECNVGEAVGIIAAQSIG
EPGTQLTMRTGEDITQGLPRVEELFEARKPKGLAIISEIKGTVKISETKK
KREIVVTSEDGETRSYLIPYGSRIKVSDGDQVEAGDELTEGSVNPHDILK
IKGVEAVQTYLVHEVQKVYRMQGVDINDKHIEVIVRQMLRKVKVEDPGDT
SLLPGGLVDVFDFEEENAKAIAEGKKPAVAKRALLGITKAALATDSFLSA
ASFQETTRVLTEAAIKGKVDPLVGLKENVIIGKLIPAGTGMSRYKDITIS
TV
3D structure
PDB8i24 Structure of the transcription open complex of distinct sigmaI factors
ChainD
Resolution3.36 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D R100 R326 R962 K965 R73 R299 R928 K931
BS02 dna D I133 R323 R351 T793 A794 Y798 Q1138 E1139 I106 R296 R324 T766 A767 Y771 Q1104 E1105
BS03 ZN D C891 C901 C864 C874
BS04 ZN D C85 C98 C58 C71
BS05 MG D D472 D474 D445 D447
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8i24, PDBe:8i24, PDBj:8i24
PDBsum8i24
PubMed37833284
UniProtA3DIZ5|RPOC_ACET2 DNA-directed RNA polymerase subunit beta' (Gene Name=rpoC)

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