Structure of PDB 8i09 Chain D

Receptor sequence
>8i09D (length=246) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence]
PCEELEIVWKNIKAEARALADCEPMLASFYHATLLKHENLGSALSYMLAN
KLASPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTP
LLYLKGFHALQAYRIGHWLWNKGRRALAIFLQNQVSVSFQVDIHPAAKIG
RGIMLDHATGIVVGETAVIEDDVSILQSVTLGGTGKTSGDRHPKIREGVM
IGAGAKILGNIEVGRGAKIGAGSVVLQPVPPHTTAAGVPARIVGKP
3D structure
PDB8i09 Alkyl gallates inhibit serine O -acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics.
ChainD
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.30: serine O-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CYS D D92 P93 D157 H158 D91 P92 D156 H157
BS02 NF0 D M201 G203 K219 I220 G221 A222 A237 M200 G202 K218 I219 G220 A221 A236
BS03 NF0 D G184 T185 G186 L227 G183 T184 G185 L226
BS04 CYS D R192 H193 R191 H192
Gene Ontology
Molecular Function
GO:0009001 serine O-acetyltransferase activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0008652 amino acid biosynthetic process
GO:0019344 cysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8i09, PDBe:8i09, PDBj:8i09
PDBsum8i09
PubMed37965540
UniProtA0A0D6I3Y9

[Back to BioLiP]