Structure of PDB 8hsa Chain D

Receptor sequence
>8hsaD (length=248) Species: 224914 (Brucella melitensis bv. 1 str. 16M) [Search protein sequence]
SPFHLNDAVAIVTGAAAGIGRAIAGTFAKAGASVVVTDLKSEGAEAVAAA
IRQAGGKAIGLECNVTDEQHREAVIKAALDQFGKITVLVNNAGGGGPKPF
DMPMSDFEWAFKLNLFSLFRLSQLAAPHMQKAGGGAILNISSIAGENTNV
RMASYGSSKAAVNHLTRNIAFDVGPMGIRVNAIAPGAMKTDALATVLTPE
IERAMLKHTPLGRLGEAQDIANAALFLCSPAAAWISGQVLTVSGGGVQ
3D structure
PDB8hsa Structure of 7-alpha-hydroxysteroid dehydrogenase
ChainD
Resolution3.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.1.1.159: 7alpha-hydroxysteroid dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD D G67 I72 D91 L92 N117 V118 N144 G146 I193 S194 S195 Y208 K212 G239 M241 G14 I19 D38 L39 N64 V65 N91 G93 I140 S141 S142 Y155 K159 G186 M188
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:8hsa, PDBe:8hsa, PDBj:8hsa
PDBsum8hsa
PubMed
UniProtQ8YIN7

[Back to BioLiP]