Structure of PDB 8hgk Chain D

Receptor sequence
>8hgkD (length=177) Species: 9606 (Homo sapiens) [Search protein sequence]
LIPIVVEQGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSES
NKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLA
AGTPGMRHSLPNSRIMIHQPIQAEEIMKLKKQLYNIYAKHTKQSLQVIES
AMERDRYMSPMEAQEFGILDKVLVHPP
3D structure
PDB8hgk Crystal structure of human ClpP in complex with ZK53
ChainD
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.21.92: endopeptidase Clp.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZLL D E82 Y118 W146 V148 L170 E22 Y58 W86 V88 L110
BS02 ZLL D S108 T135 Y138 S48 T75 Y78
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8hgk, PDBe:8hgk, PDBj:8hgk
PDBsum8hgk
PubMed37923710
UniProtQ16740|CLPP_HUMAN ATP-dependent Clp protease proteolytic subunit, mitochondrial (Gene Name=CLPP)

[Back to BioLiP]