Structure of PDB 8hfp Chain D

Receptor sequence
>8hfpD (length=83) Species: 9606 (Homo sapiens) [Search protein sequence]
LSYQSHDCSGACLNPLQLPIKCHFQRRHAKTNSHSSALHVSYKTPCGRSL
RNVEEVFRYLLETECNFLFTDNFSFNTYVQLAR
3D structure
PDB8hfp Structural Evidence for Protein Binding by the Methyl-CpG-Binding Domain of SETDB Proteins
ChainD
Resolution1.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.366: [histone H3]-N(6),N(6)-dimethyl-lysine(9) N-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D H14 C16 C20 C64 H6 C8 C12 C46
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:8hfp, PDBe:8hfp, PDBj:8hfp
PDBsum8hfp
PubMed38159574
UniProtQ96T68|SETB2_HUMAN Histone-lysine N-methyltransferase SETDB2 (Gene Name=SETDB2)

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