Structure of PDB 8gpn Chain D

Receptor sequence
>8gpnD (length=93) Species: 8355 (Xenopus laevis) [Search protein sequence]
SRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSA
3D structure
PDB8gpn Menin "reads" H3K79me2 mark in a nucleosomal context.
ChainD
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D Y42 I54 S56 R86 S87 T88 Y11 I23 S25 R55 S56 T57
BS02 dna D R33 K34 Y40 R2 K3 Y9
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:8gpn, PDBe:8gpn, PDBj:8gpn
PDBsum8gpn
PubMed36795828
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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