Structure of PDB 8fm2 Chain D

Receptor sequence
>8fm2D (length=335) Species: 587638 (HIV-1 06TG.HT008) [Search protein sequence]
KTTLFCASDAKAYEKEVHNVWATHACVPTDPNPQEMVLANVTENFNMWKN
DMVEQMHEDIISLWDESLKPCVKLTGGSAITQACPKVSFDPIPLHYCAPA
GFAILKCNNKTFNGTGPCRNVSTVQCTHGIKPVVSTQLLLNGSLAEEEII
IRSENLTNNAKTIIVHLNESVNIVCTRPNNIRQAHCNINESKWNNTLQKV
GEELAKHFPSKTIKFEPSSGGDLEITTHSFNCRGEFFYCNTSDLFNGTYR
NGTYNHTGRSSNGTITLQCKIKQIINMWQEVGRAIYAPPIEGEITCNSNI
TGLLLLRDDTETFRPGGGDMRDNWRSELYKYKVVE
3D structure
PDB8fm2 Indoline CD4-mimetic compounds mediate potent and broad HIV-1 inhibition and sensitization to antibody-dependent cellular cytotoxicity.
ChainD
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Y1X D V255 E370 S375 F376 F382 I424 N425 M426 W427 E429 V430 G431 G473 M475 V134 E224 S229 F230 F236 I275 N276 M277 W278 E280 V281 G282 G318 M320
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:8fm2, PDBe:8fm2, PDBj:8fm2
PDBsum8fm2
PubMed36961924
UniProtC6G099

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