Structure of PDB 8fhk Chain D

Receptor sequence
>8fhkD (length=645) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
KIGKTLWRYALLYRKLLITAVLLLTVAVGAELTGPFIGKKMIDDHILGIE
KTWYAVQFHGVSYVREDRLQEPVSKAKEAHIYQVGMAFYFVDQAGNRTVG
KLTITNSRAYAAEKLTKQELFQFYQPEIKGMVLLIALYGGLLVFSVFFQY
GQHYLLQMSANRIIQKMRQDVFSHIQKMPIRYFDNLPAGKVVARITNDTE
AIRDLYVTVLSTFVTSGIYMFGIFTALFLLDVKLAFVALAIVPIIWLWSV
IYRRYASYYNQKIRSINSDINAKMNESIQGMTIIQAFRHQKETMREFEEL
NESHFYFQNRMLNLNSLMSHNLVNVIRNLAFVALIWHFGGASLNAAGIVS
IGVLYAFVDYLNRLFQPITGIVNQFSKLELARVSAGRVFELLEEKNTEEA
GEPAKERALGRVEFRDVSFAYQEGEEVLKHISFTAQKGETVALVGHTGSG
KSSILNLLFRFYDAQKGDVLIDGKSIYNMSRQELRSHMGIVLQDPYLFSG
TIGSNVSLDDERMTEEEIKNALRQVGAEPLLKKLPKGINEPVIEKGSTLS
SGERQLISFARALAFDPAILILDQATAHIDTETEAVIQKALDVVKQGRTT
FVIAHRLSTIRNADQILVLDKGEIVERGNHEELMALEGQYYQMYE
3D structure
PDB8fhk Asymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter.
ChainD
Resolution2.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 7.6.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP D Y439 E443 V445 T465 G466 G468 K469 S470 H623 Y421 E425 V427 T447 G448 G450 K451 S452 H605
BS02 ATP D S565 T566 S568 G570 E571 S547 T548 S550 G552 E553
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0034040 ATPase-coupled lipid transmembrane transporter activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0006869 lipid transport
GO:0046677 response to antibiotic
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8fhk, PDBe:8fhk, PDBj:8fhk
PDBsum8fhk
PubMed37938578
UniProtO07549|YHEH_BACSU Probable multidrug resistance ABC transporter ATP-binding/permease protein YheH (Gene Name=yheH)

[Back to BioLiP]