Structure of PDB 8epx Chain D

Receptor sequence

>8epxD (length=506) Species: 2070761 (Paucibacter aquatile) [Search protein sequence]

PYDHNAEADFAASEVARMLVADPGLCYDAASLPASISASASYEPSAAGWP
KADGLVSVLEGGTSTQRAIALEYKRPQEGIHGLLTAIGQAHGYLHKGYSG
AAIVIPGRYSSHPTPAEYVRDVLNAISGSRAIAVFSYSPPDTTSPTPFAG
RIQCVRPLVFDVHLRPANQGPKTQWVHMREGSTTRDAFFRFLQVAKRLSA
DPTAPRPTLRSELVAAIGRLAPGRDPIEYITNTADNKFLTKVWQFFWLEW
LATPAVLTPWKLEAGVYSAPGARTRILREDGTDFSQLWEGRVNSLKETIA
GMLNRGEISEAQGWEAFVGGISATGGGQDKQGVRARAHSYREDIDSALAQ
LRWIEDDGLPTDQGYRFMTICERYGGANSRAAIDYMGATLIQTGRYASFL
HYINRLSERKFAENPLAYTKPGPGGMPVFTEESYWEYLQDLETKLTDELR
VMRKVSGRARPRVRTTFQVELTLLRNYGFVSSTRHRLGVGIPIDWEQVVQ
ALNVDL

3D structure

PDB

8epx Structures, activity and mechanism of the Type IIS restriction endonuclease PaqCI.

Chain

Resolution

3.15 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	D	Y3 S46 I81 H82 T177 H181 R183 V296 H342 E346 D347 S350 K458 V459 R462 R464 P465 R466 V467 R468	Y2 S45 I80 H81 T173 H177 R179 V292 H338 E342 D343 S346 K454 V455 R458 R460 P461 R462 V463 R464
BS02	dna	D	W50 E184 D284 Q290 W292 R295 D333 Q335 R340 S343 E435 W439 V459 S460 R462 T476 R488	W49 E180 D280 Q286 W288 R291 D329 Q331 R336 S339 E431 W435 V455 S456 R458 T472 R484
BS03	CA	D	H5 D54 E73 Y74	H4 D53 E72 Y73

External links

PDB	RCSB:8epx, PDBe:8epx, PDBj:8epx
PDBsum	8epx
PubMed	36987874
UniProt	A0A2N8KYF9

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