Structure of PDB 8efn Chain D

Receptor sequence
>8efnD (length=175) Species: 50429 (Stylophora pistillata) [Search protein sequence]
NVADGFAWNYYFGYLKLVLPRLEAQIAKSSEFRYKITKKKLYILVPKTCY
VYDNIADADPRVTWAGDLTPCKINRGGIKERIYKQAVYRVAMTDKHEYFF
ILEYASNLMSLYDMSLHEDAPLSRQERDDQVVLFIRKLREILEGCKECRG
KCEIVPISGDEKSKIADVLVAIHNA
3D structure
PDB8efn cGLRs are a diverse family of pattern recognition receptors in innate immunity.
ChainD
Resolution1.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4BW D N178 Y179 Y183 R250 Y252 K253 E272 S275 N276 N9 Y10 Y14 R81 Y83 K84 E103 S106 N107
Gene Ontology
Biological Process
GO:0002218 activation of innate immune response
GO:0032481 positive regulation of type I interferon production

View graph for
Biological Process
External links
PDB RCSB:8efn, PDBe:8efn, PDBj:8efn
PDBsum8efn
PubMed37379839
UniProtA0A2B4SES9|STNG3_STYPI Stimulator of interferon genes protein 3 (Gene Name=STING3)

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