Structure of PDB 8dy7 Chain D

Receptor sequence
>8dy7D (length=1253) Species: 54571 (Streptomyces venezuelae) [Search protein sequence]
DDVNFFDELRIGLATADDIRQWSHGEVKKPETINYRTLKPEKDGLFCEKI
FGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPV
THIWYFKGVPSRLGYLLDLAPKDLEKVIYFAAYMITYVDDERRTRDLPSL
EAHVSVERQQIENRRDSDLEARAKKLENDLGELEAEGAKADVRRKVREGA
EREMKQLRDRAQREIDRLDEVWSRFKNLKVQDLEGDELLYRELRDRFGTY
FDGSMGAAALQKRLESFDLEEEAERLREIIRTGKGQKKTRALKRLKVVSA
FLQTANSPKGMVLDCVPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRN
NRLKRLLDLGAPEIIVNNEKRMLQEAVDALFDNGRRGRPVTGPGNRPLKS
LSDMLKGKQGRFRQNLLGKRVDYSARSVIVVGPQLKLHQCGLPKAMALEL
FKPFVMKRLVDLNHAQNIKSAKRMVERGRTVVYDVLEEVIAEHPVLLNRA
PTLHRLGIQAFEPQLVEGKAIQIHPLVCTAFNADFDGDQMAVHLPLSAEA
QAEARILMLSSNNILKPADGRPVTMPTQDMVLGLFFLTTDGELRDTKGEG
RAFGSTAEAIMAFDAGELALQSQIDIRFPVGTVAPRGWVPPVTEEGEPEW
QQGDSFRLRTSLGRALFNELLPEDYPFVDYSVGKKQLSEIVNDLAERYPK
VIVAATLDNLKAAGFYWATRSGVTVAISDVVVPEAKKAIVKGYEEQDEKV
QKQYERGLITKEERTQELIAIWTKATNEVAEAMNANFPKTNPIFMMVDSG
ARGNMMQMRQIAGMRGLVSNAKNETIPRPIKASFREGLTVLEYFISTHGA
RKGLADTALRTADSGYLTRRLVDVSQDVIIREEDCGTERGLKLRIAERGA
DGVLRKTDDVETSVYARMLAEDVVVDGKVIAPANVDLGDVLIDALVGAGV
EEVKTRSVLTCESAVGTCAFCYGRSLATGKLVDIGEAVGIIAAQSIGEPG
TQLTMDITQGLPRVVELFEARQPKGVAPISEAAGRVRIEETEKTKKIVVT
PDDGTDETAFPISKRARLLVGEGDHVEVGQKLTVGATNPHDVLRILGQRA
VQVHLVAEVQKVYNSQGVSIHDKHIEIIIRQMLRRVTIIESGDAELLPGE
LVERSKFETENRRVVTEGGHPASGRPQLMGITKASLATESWLSAASFQET
TRVLTDAAINAKSDSLIGLKENVIIGKLIPAGTGLSRYRNIRVEPTEEAK
AAM
3D structure
PDB8dy7 Structural basis of dual activation of cell division by the actinobacterial transcription factors WhiA and WhiB.
ChainD
Resolution3.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D Q1210 E1211 Q1198 E1199
BS02 ZN D C886 C972 C885 C971
BS03 ZN D C60 C75 C59 C74
BS04 MG D D535 D537 D539 D534 D536 D538
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8dy7, PDBe:8dy7, PDBj:8dy7
PDBsum8dy7
PubMed36888660
UniProtF2RIS6

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