Structure of PDB 8ct0 Chain D

Receptor sequence
>8ct0D (length=172) Species: 1894 (Kitasatospora aureofaciens) [Search protein sequence]
PLSLPLDLAPGLVDGDTFLSIMGALPTGVTVVTTLGPDGEPYGLTCSAAC
SVSKAPPLLLVCINRDSRVLKALLERGEFAVNVLRGGGESTSARFAAPVD
DRFRDVRWEPGSAGGVPVMSADVVAHAECRVAAALDAGDHTIVIGAVVAG
GPRPEVPSPLMYWRRSYARWPV
3D structure
PDB8ct0 Crystal structures and complex formation of halogenase CtcP and FAD reductase CtcQ from the chlortetracycline biosynthetic pathway
ChainD
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.5.1.36: flavin reductase (NADH).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD D L48 T49 C50 S51 A52 C66 I67 N68 S71 R72 V73 A100 P102 D104 R106 L44 T45 C46 S47 A48 C62 I63 N64 S67 R68 V69 A96 P98 D100 R102
BS02 FAD D L23 N68 H144 Y166 R169 L19 N64 H140 Y162 R165
Gene Ontology
Molecular Function
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
GO:0036382 flavin reductase (NADH) activity
GO:0042602 riboflavin reductase (NADPH) activity

View graph for
Molecular Function
External links
PDB RCSB:8ct0, PDBe:8ct0, PDBj:8ct0
PDBsum8ct0
PubMed
UniProtS4S3E3|CTCQ_KITAU Flavin reductase (NADH) (Gene Name=ctcQ)

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