Structure of PDB 8cbn Chain D

Receptor sequence
>8cbnD (length=94) Species: 8355 (Xenopus laevis) [Search protein sequence]
TRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRLA
HYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
3D structure
PDB8cbn Multivalency of nucleosome recognition by LEDGF.
ChainD
Resolution3.34 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna D T29 S53 R83 S84 T85 T1 S25 R55 S56 T57
BS02 dna D R30 K31 E32 S33 I36 Y37 R2 K3 E4 S5 I8 Y9
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8cbn, PDBe:8cbn, PDBj:8cbn
PDBsum8cbn
PubMed37615563
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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