Structure of PDB 8bsu Chain D

Receptor sequence
>8bsuD (length=253) Species: 10116 (Rattus norvegicus) [Search protein sequence]
RSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEI
RLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITAVREKAIDFSK
PFMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKIST
FEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNL
TQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGS
GCP
3D structure
PDB8bsu Positive allosteric modulation of homomeric kainate receptors GluK1-3
ChainD
Resolution2.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2J9 D P106 S214 K215 G216 P101 S209 K210 G211
BS02 2J9 D K105 P106 F107 M108 T109 L236 K100 P101 F102 M103 T104 L231
BS03 ZN D D242 H245 D237 H240
BS04 KAI D E15 Y63 P90 T92 R97 G142 A143 T144 E191 E10 Y58 P85 T87 R92 G137 A138 T139 E186
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8bsu, PDBe:8bsu, PDBj:8bsu
PDBsum8bsu
PubMed38145505
UniProtP42264|GRIK3_RAT Glutamate receptor ionotropic, kainate 3 (Gene Name=Grik3)

[Back to BioLiP]