Structure of PDB 8brn Chain D

Receptor sequence
>8brnD (length=426) Species: 3885 (Phaseolus vulgaris) [Search protein sequence]
TNKNRDMPLDSDVFRVPPGYNAPQQVHITQGDLVGRAMIISWVTMDEPGS
SAVRYWSEKNGRKRIAKGKMSTYRFFNYSSGFIHHTTIRKLKYNTKYYYE
VGLRNTTRRFSFITPPQTGLDVPYTFGLIGDLGQSFDSNTTLSHYELSPK
KGQTVLFVGDLSYADRYPNHDNVRWDTWGRFTERSVAYQPWIWTAGNHEI
EFAPEINETEPFKPFSYRYHVPYEASQSTSPFWYSIKRASAHIIVLSSYS
AYGRGTPQYTWLKKELRKVKRSETPWLIVLMHSPLYNSYNHHFMEGEAMR
TKFEAWFVKYKVDVVFAGHVHAYERSERVSNIAYKITNGLCTPVKDQSAP
VYITIGDAGNYGVIDSNMIQPQPEYSAFREASFGHGMFDIKNRTHAHFSW
NRNQDGVAVEADSVWFFNRHWYPVDD
3D structure
PDB8brn Optimization of an alpha-aminonaphthylmethylphosphonic acid inhibitor of purple acid phosphatase using rational structure-based design approaches.
ChainD
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.2: acid phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D D164 N201 H286 H323 D160 N197 H282 H319
BS02 FE D D135 D164 Y167 H325 D131 D160 Y163 H321
BS03 R9X D D169 R170 N201 H202 H295 H296 H323 H325 Y365 D165 R166 N197 H198 H291 H292 H319 H321 Y361
Gene Ontology
Molecular Function
GO:0003993 acid phosphatase activity
GO:0008199 ferric iron binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:8brn, PDBe:8brn, PDBj:8brn
PDBsum8brn
PubMed37087894
UniProtP80366|PPAF_PHAVU Fe(3+)-Zn(2+) purple acid phosphatase

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