Structure of PDB 8bo1 Chain D

Receptor sequence
>8bo1D (length=396) Species: 28173 (Vibrio nigripulchritudo) [Search protein sequence]
KTYQSRDLVLEPIQHPKSIELGMPEVDQSVLAEVAERENVIIGVRPVDEK
SKSLIASKMYSSKGLFVKAKSSDWGPMSGFIPVDQSFAKASARRDLEKFN
EYAEQSILSGNAVSANLYLNQVRIEELVSKYESLTPLELDVDSGMYKTTA
TNGDQTIPFFLNKVTVDDKELWQVHYLREGELAPFKVIGDPVSKQPMTAD
YDLLTVMYTYGDLGPQDKVKQPLTWEQWKESVTYEDLSPKYKARYDNQAL
YEKQDGASLGMVSDRLKELKDVINTSLGRTDGLEMVHHGADDANPYAVMA
DNFPATFFVPKHFFDDDGLGEGKGSIQTYFNVNEQGAVVIQNPQEFSNFQ
QVAINASYRASLNDKWNSGLDSPLFTTKRKLSHDYLDARDEVAKKL
3D structure
PDB8bo1 Functional and structural insights into the multi-step activation and catalytic mechanism of bacterial ExoY nucleotidyl cyclase toxins bound to actin-profilin.
ChainD
Resolution2.501 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.6.1.1: adenylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3AT D R510 K528 L530 K533 K535 S536 K554 D665 D667 G725 M726 H753 G754 N759 R45 K63 L65 K68 K70 S71 K89 D200 D202 G260 M261 H288 G289 N294
BS02 MN D D665 D667 D200 D202
BS03 MG D D665 D667 D200 D202
BS04 MN D D665 D667 H753 D200 D202 H288
BS05 MG D D665 D667 H753 D200 D202 H288
Gene Ontology
Molecular Function
GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:8bo1, PDBe:8bo1, PDBj:8bo1
PDBsum8bo1
PubMed37747912
UniProtA0A9P1NJI6

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