Structure of PDB 8bav Chain D

Receptor sequence
>8bavD (length=257) Species: 9606 (Homo sapiens) [Search protein sequence]
LDAAGFWQVWQRFDADEKGYIEEKELDAFFLHMLMKLGTDDTVMKANLHK
VKQQFMTTIRMKELAGMFLSEDENFLLLFRRENPLDSSVEFMQIWRKYDA
DSSGFISAAELRNFLRDLFLHHKKAISEAKLEEYTGTMMKIFDRNKDGRL
DLNDLARILALQENFLLQFKMDACSTEERKRDFEKIFAYYDVSKTGALEG
PEVDGFVKDMMELVQPSISGVDLDKFREILLRHCDVNKDGKIQKSELALC
LGLKINP
3D structure
PDB8bav Calmodulin type regulator (Homo sapiens) with peptide ligand
ChainD
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA D D118 D120 S122 F124 E129 D99 D101 S103 F105 E110
BS02 CA D D162 N164 D166 R168 D143 N145 D147 R149
BS03 CA D D210 S212 T214 A216 E218 E221 D191 S193 T195 A197 E199 E202
BS04 CA D D254 N256 D258 K260 Q262 E265 D235 N237 D239 K241 Q243 E246
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0008150 biological_process
GO:0099509 regulation of presynaptic cytosolic calcium ion concentration
GO:1900271 regulation of long-term synaptic potentiation
Cellular Component
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016020 membrane
GO:0030425 dendrite
GO:0030658 transport vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0043195 terminal bouton
GO:0045202 synapse

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8bav, PDBe:8bav, PDBj:8bav
PDBsum8bav
PubMed38593081
UniProtO76038|SEGN_HUMAN Secretagogin (Gene Name=SCGN)

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