Structure of PDB 8ajj Chain D

Receptor sequence
>8ajjD (length=397) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
TYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSNYHLLADDNNIDVLDFK
AQFKSNTEVNLLDQHDDIVDSITAPHIIINTGATSVIPNIKGLDQAKHVF
DSTGLLNISYQPKHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPR
EDQDVVAYGITDLENKGIALHTNVETTELSSDNHHTTVHTNVDNFEADAV
LLAIGRKPNTDLALENTDIELGDRGEIKVNAHLQTTVPHIYAAGDVKGGL
QFTYISLDDYRIIKSALYGNQSRTTDNRGSVPYTVFIDPPLSRVGLTSKE
AAAQHYDYTEHQLLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGK
QSEELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLFNFHHHHH
3D structure
PDB8ajj MerA functions as a hypothiocyanous acid reductase and defense mechanism in Staphylococcus aureus.
ChainD
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.-.-.-
1.16.1.1: mercury(II) reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD D G10 F11 G12 I32 E33 Q34 A99 N128 T129 G130 G292 D293 Q299 F300 T301 Y302 S304 G8 F9 G10 I30 E31 Q32 A51 N80 T81 G82 G244 D245 Q251 F252 T253 Y254 S256
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004791 thioredoxin-disulfide reductase (NADPH) activity
GO:0016491 oxidoreductase activity
GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
Biological Process
GO:0045454 cell redox homeostasis
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8ajj, PDBe:8ajj, PDBj:8ajj
PDBsum8ajj
PubMed36779383
UniProtQ2G0I4

[Back to BioLiP]