Structure of PDB 8a4b Chain D

Receptor sequence
>8a4bD (length=169) Species: 9606 (Homo sapiens) [Search protein sequence]
FDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHE
KRVKLQIWDTAGLERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWAT
QIKTYSWDNAQVILVGNKCDMEEERVVPTEKGQLLAEQLGFDFFEASAKE
NISVRQAFERLVDAICDKM
3D structure
PDB8a4b Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector.
ChainD
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP D S31 S32 V33 G34 K35 T36 S37 F47 P49 F51 S53 T54 A79 G80 N135 K136 D138 M139 S165 A166 K167 S13 S14 V15 G16 K17 T18 S19 F29 P31 F33 S35 T36 A61 G62 N117 K118 D120 M121 S147 A148 K149
BS02 MG D T36 T54 T18 T36
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:8a4b, PDBe:8a4b, PDBj:8a4b
PDBsum8a4b
PubMed35871249
UniProtP20337|RAB3B_HUMAN Ras-related protein Rab-3B (Gene Name=RAB3B)

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