Structure of PDB 7zj3 Chain D

Receptor sequence
>7zj3D (length=85) Species: 9606 (Homo sapiens) [Search protein sequence]
PSPVVRQIDKQFLICSICLERYKNPKVLPCLHTFCERCLQNYIPAHSLTL
SCPVCRQTSILPEKGVAALQNNFFITNLMDVLQRT
3D structure
PDB7zj3 Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity.
ChainD
Resolution2.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN D C23 C26 C43 C46 C15 C18 C35 C38
BS02 ZN D C38 H40 C60 C63 C30 H32 C52 C55
External links
PDB RCSB:7zj3, PDBe:7zj3, PDBj:7zj3
PDBsum7zj3
PubMed36481767
UniProtQ9C040|TRIM2_HUMAN Tripartite motif-containing protein 2 (Gene Name=TRIM2)

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