Structure of PDB 7zdc Chain D

Receptor sequence
>7zdcD (length=586) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
KSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHM
IMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQV
LDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPL
LIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLS
GHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGI
LEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQ
PLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELASTDPVTIEA
EELFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSY
QGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASE
QELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLN
PCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDV
IWVMQDGRIIEQGRYAELSVAGGPFATLLAHRQEEI
3D structure
PDB7zdc IF(heme/confined) conformation of CydDC in ADP(CydD) bound state (Dataset-3)
ChainD
Resolution3.13 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.4.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEB D N191 N194 F195 F247 G308 T309 Y311 H312 N189 N192 F193 F245 G306 T307 Y309 H310
BS02 MG D S390 Q430 S388 Q428
BS03 ADP D S359 K363 L365 G386 S387 G388 K389 S390 S391 S357 K361 L363 G384 S385 G386 K387 S388 S389
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0015439 ABC-type heme transporter activity
GO:0016887 ATP hydrolysis activity
GO:0034040 ATPase-coupled lipid transmembrane transporter activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0006865 amino acid transport
GO:0006869 lipid transport
GO:0033228 cysteine export across plasma membrane
GO:0034775 glutathione transmembrane transport
GO:0035351 heme transmembrane transport
GO:0042883 cysteine transport
GO:0045454 cell redox homeostasis
GO:0055085 transmembrane transport
GO:1903605 cytochrome biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055051 ATP-binding cassette (ABC) transporter complex, integrated substrate binding

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zdc, PDBe:7zdc, PDBj:7zdc
PDBsum7zdc
PubMed37095238
UniProtP29018|CYDD_ECOLI Glutathione/L-cysteine transport system ATP-binding/permease protein CydD (Gene Name=cydD)

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