Structure of PDB 7z0q Chain D

Receptor sequence
>7z0qD (length=176) Species: 9606 (Homo sapiens) [Search protein sequence]
QPRFLWQGKYKCHFFNGTERVQFLERLFYNQEEFVRFDSDVGEYRAVTEL
GRPVAESWNSQKDILEDRRGQVDTVCRHNYGVGESFTVQRRVHPEVTVYP
AHNLLVCSVSGFYPGSIEVRWFGQEEKAGVVSTGLIQNGDWTFQTLVMLE
TVPEVYTCQVEHPSVMSPLTVEWRAR
3D structure
PDB7z0q MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
ChainD
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D Y13 Y47 W61 R71 Q74 T77 H81 N82 V85 Y10 Y44 W58 R68 Q71 T74 H78 N79 V82
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7z0q, PDBe:7z0q, PDBj:7z0q
PDBsum7z0q
PubMed37142807
UniProtD7RIG5

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