Structure of PDB 7yxb Chain D

Receptor sequence
>7yxbD (length=192) Species: 9606 (Homo sapiens) [Search protein sequence]
DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVT
ELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTV
YPAKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNG
DWTFQTLVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRARSE
3D structure
PDB7yxb MHC-II dynamics are maintained in HLA-DR allotypes to ensure catalyzed peptide exchange.
ChainD
Resolution2.095 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D H13 Y30 Y37 P56 D57 W61 L67 Y78 H81 N82 V85 H12 Y29 Y36 P55 D56 W60 L66 Y77 H80 N81 V84
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7yxb, PDBe:7yxb, PDBj:7yxb
PDBsum7yxb
PubMed37142807
UniProtA0A1V1IGJ9

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