Structure of PDB 7yi4 Chain D

Receptor sequence
>7yi4D (length=316) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
TISEDSKVSVTGLPLNKGPSEKIKRESLWNDLKTFLTENMTEESNIRSTI
GWNEDFCSACNQSGSFLCCDTCPKSFHFLCLDPPIDPNNLPKGDWHCNEC
KFKIFINNSMATLKKIESNFIKQNNNVKIFAKLLFNIDSHNPKQFQLPNY
IKETFPAVKTGSRGQYSDENDKSYNPDTHIDSNSGKFLICYKCNQTRLGS
WSHPENSRLIMTCDYCQTPWHLDCVPRASFKNLGSKWKCPLHSPTKVYKK
YKVWKKQRLINKKNQLYYEPLQKIGYQNNGNIQIINQDFKITQIDENSIK
YDFFDKIYKSKMVQKR
3D structure
PDB7yi4 Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
ChainD
Resolution3.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D K548 F552 Y556 K300 F304 Y308
BS02 ZN D C417 C420 H448 C451 C190 C193 H221 C224
BS03 ZN D C263 C266 H283 C286 C57 C60 H77 C80
BS04 ZN D C275 C278 C303 C306 C69 C72 C97 C100
BS05 ZN D C443 C466 H469 C216 C239 H242
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0030174 regulation of DNA-templated DNA replication initiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060195 negative regulation of antisense RNA transcription
Cellular Component
GO:0000118 histone deacetylase complex
GO:0005634 nucleus
GO:0032221 Rpd3S complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7yi4, PDBe:7yi4, PDBj:7yi4
PDBsum7yi4
PubMed37468628
UniProtQ04779|RCO1_YEAST Transcriptional regulatory protein RCO1 (Gene Name=RCO1)

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