Structure of PDB 7yi0 Chain D

Receptor sequence
>7yi0D (length=311) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
KVSVTGLPLNKGPSEKIKRESLWNDLKTFLTENMTEESNIRSTIGWNEDF
CSACNQSGSFLCCDTCPKSFHFLCLDPPIDPNNLPKGDWHCNECKFKIFI
NNSMATLKKIESNFIKQNNNVKIFAKLLFNIDSHNPKQFQLPNYIKETFP
AVKTGSRGQYSDENDKSYNPDTHIDSNSGKFLICYKCNQTRLGSWSHPEN
SRLIMTCDYCQTPWHLDCVPRASFKNLGSKWKCPLHSPTKVYKKYKVWKK
QRLINKKNQLYYEPLQKIGYQNNGNIQIINQDFKITQIDENSIKYDFFDK
IYKSKMVQKRK
3D structure
PDB7yi0 Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S.
ChainD
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN D C263 H283 C286 C51 H71 C74
BS02 ZN D C275 C306 C63 C94
BS03 ZN D C440 C466 H469 C207 C233 H236
BS04 ZN D C417 C420 H448 C451 C184 C187 H215 C218
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0030174 regulation of DNA-templated DNA replication initiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060195 negative regulation of antisense RNA transcription
Cellular Component
GO:0000118 histone deacetylase complex
GO:0005634 nucleus
GO:0032221 Rpd3S complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7yi0, PDBe:7yi0, PDBj:7yi0
PDBsum7yi0
PubMed37468628
UniProtQ04779|RCO1_YEAST Transcriptional regulatory protein RCO1 (Gene Name=RCO1)

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