Structure of PDB 7yhs Chain D

Receptor sequence

>7yhsD (length=324) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]

LSTASVLAFERKLDPSDALMSAGAWAQRDASQEWPAVTVREKSVRGTISN
RLKTKDRDPAKLDASIQSPNLQTVDVANLPSDADTLKVRFTLRVLGGAGT
PSACNDAAYRDKLLQTVATYVNEQGFAELARRYAHNLANARFLWRNRVGA
EAVEVRINHIRQGEVARTWRFDALAIGLRDFKADAELDALAELIASGLSG
SGHVLLEVVAFARIGDGQEVFPSQELIKSKTLYSVRDAAAIHSQKIGNAL
RTIDTWYPDEDGLGPIAVEPYGSVTSQGKAYRQPKQKLDFYTLLDNWVLR
DEAPAVEQQHYVIANLIRGGVFGE

3D structure

PDB

7yhs Anti-CRISPR protein AcrIF4 inhibits the type I-F CRISPR-Cas surveillance complex by blocking nuclease recruitment and DNA cleavage.

Chain

Resolution

3.37 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	D	F33 E34 R35 S67 R69 G70 L95 S247 Q248 E249 H275 Q277 K278 N281 S309 G352 G353 V354	F9 E10 R11 S43 R45 G46 L71 S223 Q224 E225 H242 Q244 K245 N248 S276 G319 G320 V321

External links

PDB	RCSB:7yhs, PDBe:7yhs, PDBj:7yhs
PDBsum	7yhs
PubMed	36209819

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