Structure of PDB 7yfl Chain D

Receptor sequence
>7yflD (length=679) Species: 9606 (Homo sapiens) [Search protein sequence]
AAEAARLGPAVAAAVRSPGLDVRPVALVLNGSDPRSLVLQLCDLLSGLRV
HGVVFEDDSRAVAPILDFLSAQTLPIVAVHGAALVLTPKEKGSTFLQLGS
STEQQLQVIFEVLEEYDWTSFVAVTTRAPGHRAFLSYIEVLTDGSLVGWE
HRGALTLEAVLSAQLRSVSAQIRLLFCAREEAEPVFRAAEEAGLTGSGYV
WFMVGPQLAPLPAGLFAVRSAGWRDDLARRVAAGVAVVARGAQALLRDYG
FLPELGHDCRAQNRTHRGESLHRYFMNITWDNRDYSFNEDGFLVNPSLVV
ISLTRDRTWEVVGSWEQQTLRLKYPLWSRYGRDTQHLTVATLEERPFVIV
EPADPISGTCIRDSVPCRSQLNRPEKRCCKGFCIDILKRLAHTIGFSYDL
YLVTNGKHGKKIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVP
FVETGISVMVARPYSPAVWVMMFVMCWLLWALVFNNSVPVGTTSKIMVLV
WAFFAVIFLASYTANLAAFMIVDTVSGLSDRKFQRPQEQYPPLKFGTVPN
GSTEKNIRSNYPDMHSYMVRYNQPRVEEALTQLKAGKLDAFIYDAAVLNY
MARKDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDE
IEMLERLWLSGICHKLDIDNMAGVFYMLL
3D structure
PDB7yfl Distinct structure and gating mechanism in diverse NMDA receptors with GluN2C and GluN2D subunits.
ChainD
Resolution3.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLU D H513 T541 G716 S717 Y758 D759 H408 T436 G551 S552 Y593 D594
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0038023 signaling receptor activity
Biological Process
GO:0006811 monoatomic ion transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7yfl, PDBe:7yfl, PDBj:7yfl
PDBsum7yfl
PubMed36959261
UniProtO15399|NMDE4_HUMAN Glutamate receptor ionotropic, NMDA 2D (Gene Name=GRIN2D)

[Back to BioLiP]