Structure of PDB 7ye2 Chain D

Receptor sequence
>7ye2D (length=1140) Species: 565050 (Caulobacter vibrioides NA1000) [Search protein sequence]
TFDQIRISLASPEKIRSWSFGEIKKPETINYRTFKPERDGLFCARIFGPT
KDYECLCGKYKRMKYKGIICEKCGVEVTLARVRRERMGHIELASPVAHIW
FLKSLPSRIAMMLDMPLKDIERVLYFEYYIVTEPGPLKQHQLLSEDDYMR
AQEEYGDDSFTAEIGAEAIQNLLKAIDLEKEAERLREELSGTVSDMKQKK
FSKRLKILEAFQESGNRPEWMVLTVVPVIPPELRPLVPLDGGRFATSDLN
DLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQESVDALFDNGRRGRVI
TGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHEC
GLPKKMALELFKPFIYARLDAKGLSGTVKQSKRMVEREQPQVWDILEEVI
REHPVLLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQM
AVHVPLSLEAQLEARVLMMSTNNILSPANGRPIIVPSQDIVLGLYYLSVA
RDGEPGEGKIFADLGEIEAAMDAGVVSLHAKIKARHTEMTPEGVLLRKVI
DTTPGRMKIAALLPHHPQIGHRLIEKALTKKEIGNLIDIVYRHCGQKATV
IFADKVMGLGFKEAAKAGISFGKDDIIIPVRKTAIVEETRKLAEEYEQQY
ITKGEKYNKVVDAWAKATDRVADEMMAELQMKHKDENGREKEINAIYMMA
HSGARGSQAQMKQLGGMRGLMAKPSGEIIETPIVSNFKEGLTVQEYFNST
HGARKGLADTALKTANSGYLTRRLVDVAQDCIIVEEDCGTTKGITLRAVV
EGGDVLVSLGSRVLGRFTAEDVKDPGTGELVVPADTYIDENIADAIEAAV
VQSVKVRSVLTCEAKIGVCGACYGRDLARGTPVNIGEAVGVIAAQSIGEP
GTQLTITGGLPRVAELFEARRPKDCAVIAEMDGRVEFGKDYKNKRRIKIT
PDKHIAVHDGDYITKGEYIIDGNPDPHDILRILGVEALANFLVDEIQEVY
RLQGVPINDKHIETIVRQMLQKVEILEPGDTGLIKGDHLDKPEFDKEQEK
AIARPAVTQPVLLGITKASLQTKSFISAASFQETTRVLTEASVHGKTDTL
EGLKENVIVGRLIPAGTGSYLRSLQRVAAKRDEQLAQQRE
3D structure
PDB7ye2 Cryo-EM structures of Caulobacter crescentus transcription activation complex with an essential cell cycle regulator GcrA
ChainD
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D L121 K134 R1139 K1307 L105 K118 R920 K1067
BS02 dna D L121 D213 R261 A321 K334 K336 R354 A428 P429 T786 G790 R794 R1165 E1323 L105 D195 R243 A303 K316 K318 R336 A410 P411 T764 G768 R772 R946 E1083
BS03 ZN D C884 C894 C862 C872
BS04 ZN D L72 C86 L56 C70
BS05 MG D D462 D464 D466 D444 D446 D448
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7ye2, PDBe:7ye2, PDBj:7ye2
PDBsum7ye2
PubMed
UniProtA0A0H3C4W8

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