Structure of PDB 7xwi Chain D

Receptor sequence
>7xwiD (length=223) Species: 4929 (Meyerozyma guilliermondii) [Search protein sequence]
EQTYFISGANRGIGFSVVQRLAAKSGVKVIATARDPASATALNELAKENP
QVKVVQLDISDEESIKKIAKNVSQYTDSIDVFVSNAAIAKSFGPLLNTPR
EQWIEHFFTNVLGPIRLFQELYPLIKKGTQKKVFFISSNAGSLNLDFGLD
FSAYGQSKAALNYSTKELARQLKPENFIVAAVHPGVVTTKITPEESAAAL
CKLFESLNTTGKYLSYDGTELPW
3D structure
PDB7xwi Structure-based rational design of a short-chain dehydrogenase/reductase for improving activity toward mycotoxin patulin
ChainD
Resolution2.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.1: alcohol dehydrogenase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NDP D G9 N11 R12 R35 D59 I60 N86 A87 A88 I137 S138 S139 Y155 K159 H184 P185 G186 V187 V188 G8 N10 R11 R34 D58 I59 N85 A86 A87 I136 S137 S138 Y154 K158 H183 P184 G185 V186 V187
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

View graph for
Molecular Function
External links
PDB RCSB:7xwi, PDBe:7xwi, PDBj:7xwi
PDBsum7xwi
PubMed36176222
UniProtA0A888VSF1

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