Structure of PDB 7wnv Chain D

Receptor sequence
>7wnvD (length=226) Species: 9606 (Homo sapiens) [Search protein sequence]
ALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSG
STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKCLSDLLLEML
3D structure
PDB7wnv Structure of the ligand binding domain of estrogen receptor alpha in complex with covalent inhibitor CO9
ChainD
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2I9 D T347 A350 E353 W383 L387 I424 H524 L525 C530 T41 A44 E47 W77 L81 I117 H211 L212 C217
External links
PDB RCSB:7wnv, PDBe:7wnv, PDBj:7wnv
PDBsum7wnv
PubMed37871388
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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