Structure of PDB 7wku Chain D

Receptor sequence
>7wkuD (length=302) Species: 1586324 (Porcine deltacoronavirus) [Search protein sequence]
SAGIKILLHPSGVVERCMVSVVYNGSALNGIWLKNVVYCPRHVIGKFRGD
QWTHMVSIADCRDFIVKCPIQGIQLNVQSVKMVGALLQLTVHTNNTATPD
YKFERLQPGSSMTIACAYDGIVRHVYHVVLQLNNLIYASFLNGACGSVGY
TLKGKTLYLHYMHHIEFNNKTHSGTDLEGNFYGPYVDEEVIQQQTAFQYY
TDNVVAQLYAHLLTVDARPKWLAQSQISIEDFNSWAANNSFANFPCEQTN
MSYIMGLSQTARVPVERILNTIIQLTTNRGACIMGSYFECDWTPEMVYNQ
AP
3D structure
PDB7wku The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals.
ChainD
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.57: methyltransferase cap1.
3.4.19.12: ubiquitinyl hydrolase 1.
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D L27 H41 F139 G142 C144 H162 H163 I164 E165 F166 D186 E188 I190 L28 H42 F140 G143 C145 H163 H164 I165 E166 F167 D187 E189 I191
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0019082 viral protein processing

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:7wku, PDBe:7wku, PDBj:7wku
PDBsum7wku
PubMed35336895
UniProtA0A140ESF0

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