Structure of PDB 7wda Chain D

Receptor sequence
>7wdaD (length=426) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
QGLVVSFYTPATDGATFTAIAQRCNQQFGGRFTIAQVSLPRSPNEQRLQL
ARRLTGNDRTLDVMALDVVWTAEFAEAGWALPLSDDPAGLAENDAVADTL
PGPLATAGWNHKLYAAPVTTNTQLLWYRPDLVNSPPTDWNAMIAEAARLH
AAGEPSWIAVQANQGEGLVVWFNTLLVSAGGSVLSEDGRHVTLTDTPAHR
AATVSALQILKSVATTPGADGSARLAFEQGKAALEVNWPFVFASMLENAV
KGGVPFLPLNRIPQLAGSINDIGTFTPSDEQFRIAYDASQQVFGFAPYPA
VAPGQPAKVTIGGLNLAVAKTTRHRAEAFEAVRCLRDQHNQRYVSLEGGL
PAVRASLYSDPQFQAKYPMHAIIRQQLTDAAVRPATPVYQALSIRLAAVL
SPITEIDPESTADELAAQAQKAIDGM
3D structure
PDB7wda Structural analysis of LpqY, a substrate-binding protein from the SugABC transporter of Mycobacterium tuberculosis, provides insights into its trehalose specificity.
ChainD
Resolution1.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GLC D D97 E196 G350 G351 R421 D67 E166 G312 G313 R383
BS02 GLC D N151 W276 N121 W238
Gene Ontology
Molecular Function
GO:0015574 trehalose transmembrane transporter activity
GO:1901982 maltose binding
Biological Process
GO:0015771 trehalose transport
GO:0051701 biological process involved in interaction with host
Cellular Component
GO:0005886 plasma membrane
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:7wda, PDBe:7wda, PDBj:7wda
PDBsum7wda
PubMed35775983
UniProtP9WGU9|LPQY_MYCTU Trehalose-binding lipoprotein LpqY (Gene Name=lpqY)

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