Structure of PDB 7v97 Chain D

Receptor sequence
>7v97D (length=192) Species: 9606 (Homo sapiens) [Search protein sequence]
VPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLW
VDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIR
VEGNLRVEYLDDRNTFRHSVVVPYEPPEGSDCTTIHYNYMCNSSCMGGMN
RRPILTIITLEDSSGNLLGRNSFEMRVCACPGRDRRTEEENL
3D structure
PDB7v97 Diverse rescue potencies of p53 mutations to ATO are predetermined by intrinsic mutational properties.
ChainD
Resolution2.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ARS D C124 M133 C135 C141 C28 M37 C39 C45
BS02 ZN D C176 H179 C238 C242 C80 H83 C141 C145
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7v97, PDBe:7v97, PDBj:7v97
PDBsum7v97
PubMed37018419
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53)

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