Structure of PDB 7v2o Chain D

Receptor sequence

>7v2oD (length=208) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]

GRYIGPVCRLCRREGVKLYLKGERCYSPKCAMERRPYPPGQHGQKRARRP
SDYAVRLREKQKLRRIYGISERQFRNLFEEASKKKGVTGSVFLGLLESRL
DNVVYRLGFAVSRRQARQLVRHGHITVNGRRVDLPSYRVRPGDEIAVAEK
SRNLELIRQNLEAMKGRKVGPWLSLDVEGMKGKFLRLPDREDLALPVNEQ
LVIEFYSR

3D structure

PDB

7v2o Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases.

Chain

Resolution

3.5 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	D	G2 P7 V8 R10 R13 R14 K22 E24 R25 K30 R35 R36 Y38 G41 Q42 H43 Y54 A55 L58 R59 Q62 R65 S71 E72 R73 Q74 V112 R115 Q116 Q119 R122 H123 H125 R132 D134 L135 S137 Y138 R141 K151 L157 E205 R209	G1 P6 V7 R9 R12 R13 K21 E23 R24 K29 R34 R35 Y37 G40 Q41 H42 Y53 A54 L57 R58 Q61 R64 S70 E71 R72 Q73 V111 R114 Q115 Q118 R121 H122 H124 R131 D133 L134 S136 Y137 R140 K150 L156 E204 R208
BS02	ZN	D	C9 C12 C31	C8 C11 C30

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0019843	rRNA binding
GO:0046872	metal ion binding

	Biological Process
GO:0006412	translation
GO:0042274	ribosomal small subunit biogenesis

	Cellular Component
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7v2o, PDBe:7v2o, PDBj:7v2o
PDBsum	7v2o
PubMed	35316014
UniProt	P80373\|RS4_THET8 Small ribosomal subunit protein uS4 (Gene Name=rpsD)

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