Structure of PDB 7usq Chain D

Receptor sequence
>7usqD (length=93) Species: 9606 (Homo sapiens) [Search protein sequence]
CHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFM
HILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY
3D structure
PDB7usq Characterization of caspase-2 inhibitors based on specific sites of caspase-2-mediated proteolysis.
ChainD
Resolution2.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D Y204 S205 W206 R207 N208 S209 W214 S249 F250 F256 Y21 S22 W23 R24 N25 S26 W31 S66 F67 F73
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7usq, PDBe:7usq, PDBj:7usq
PDBsum7usq
PubMed35642311
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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