Structure of PDB 7usf Chain D

Receptor sequence
>7usfD (length=235) Species: 11757 (Mouse mammary tumor virus) [Search protein sequence]
LESAQESHALHHQNAAALRFQFHITREQAREIVKLCPNCPLKPRVLWQMD
VTHVSEFGKLKYVHVTVDTYSHFTFATARTGEATKDVLQHLAQSFAYMGI
PQKIKTDNAPAYVSRSIQEFLARWKISHVQAIVERTHQNIKAQLNKLQKY
YTPHHLLAHALFVLNHVNMDNQGHTAAERHWGPMVMWKDLLTGSWKGPDV
LITAGRGYACVFPQDAESPIWVPDRFIRPFTERKE
3D structure
PDB7usf B-to-A transition in target DNA during retroviral integration.
ChainD
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna D R240 G241 Y242 W255 R259 R206 G207 Y208 W221 R225
BS02 ZN D H9 H13 C37 C40 H8 H12 C36 C39
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:7usf, PDBe:7usf, PDBj:7usf
PDBsum7usf
PubMed35947647
UniProtP03365|POL_MMTVB Gag-Pro-Pol polyprotein (Gene Name=gag-pro-pol)

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