Structure of PDB 7uqj Chain D

Receptor sequence
>7uqjD (length=581) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
LDPLGVDMNVNFDDIGGLDNYIDQLKEMVALPLLYPELYQNFNITPPRGV
LFHGPPGTGKTLMARALAASCSSDERKITFFMRKGADILSKWVGEAERQL
RLLFEEAKKHQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLALMDGMD
NRGQVIVIGATNRPDAVDPALRRPGRFDREFYFPLPDVKARFKILQIQTR
KWSSPLSTNFIDKLAFLTKGYGGADLRSLCTEAALISIQRSFPQIYRSND
KLLVDPSKIKVKVSDFMLALKKIVPSSARSTGSSPQPLPELIKPLLADQL
NNLKNKLDYMLNIKDTTFQRNTSLLQNFIDYEEYSYEFFESMAESQICKP
RLLINGPKGNGQQYVGAAILNYLEEFNVQNLDLASLVSESSRTIEAAVVQ
SFMEAKKRQPSVVFIPNLDIWINTIPENVILVLSGLFRSLQSNEKILLLC
LAENLDISEVKNGILSDFAFDKNIFQLHKPSKENITRYFSNLIELLKTKP
SDIPMKKRRVKPLPELQKVTKELILTPEQIKKVSACLIEHCQNFTVSQLE
DVHSSVAKIIWKSKSAWDKTGTVDEIIKFLS
3D structure
PDB7uqj The Saccharomyces cerevisiae Yta7 ATPase hexamer contains a unique bromodomain tier that functions in nucleosome disassembly.
ChainD
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide D S490 K491 E532 S90 K91 E132
BS02 AGS D G416 P456 G457 T458 G459 K460 T461 L462 I594 G623 A624 R627 G16 P56 G57 T58 G59 K60 T61 L62 I194 G223 A224 R227
BS03 AGS D D547 R573 R576 D147 R173 R176
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0042393 histone binding
GO:0140658 ATP-dependent chromatin remodeler activity
GO:0140674 ATP-dependent histone chaperone activity
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006261 DNA-templated DNA replication
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0006337 nucleosome disassembly
GO:0006338 chromatin remodeling
GO:0034080 CENP-A containing chromatin assembly
GO:0045815 transcription initiation-coupled chromatin remodeling
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:2000219 positive regulation of invasive growth in response to glucose limitation
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7uqj, PDBe:7uqj, PDBj:7uqj
PDBsum7uqj
PubMed36592926
UniProtP40340|ATAD2_YEAST ATPase histone chaperone YTA7 (Gene Name=YTA7)

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