Structure of PDB 7u8r Chain D

Receptor sequence
>7u8rD (length=456) Species: 9823 (Sus scrofa) [Search protein sequence]
YITHPRVTYRTVCSVNGPLVVLDHVKFAQYAEIVNFTLPNGTQRSGQVLE
VSGTKAIVQVFEGTSGIDAQKTTCEFTGDILRTPVSEDMLGRVFNGSGKP
IDNGPVVMAEDFLDINGQPINPHDRIYPEEMIQTGISPIDVMNSIARGQK
IPIFSAAGLPHNEIAAQICRQAGLVNFAIVFAAMGVNMETARFFKSDFEE
NGTMGNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDM
SSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRGGSITQ
IPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYPPINVLPSLSR
LMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLL
YLEFLQKFERNFINQGPYEKRSVFESLDLGWKLLRIFPKEMLKRIPQSMI
DEFYSR
3D structure
PDB7u8r CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7.
ChainD
Resolution3.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP D R394 K397 R350 K353
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0016324 apical plasma membrane
GO:0033180 proton-transporting V-type ATPase, V1 domain

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7u8r, PDBe:7u8r, PDBj:7u8r
PDBsum7u8r
PubMed35794005
UniProtA0A4X1W9K3

[Back to BioLiP]