Structure of PDB 7txg Chain D

Receptor sequence
>7txgD (length=326) Species: 263 (Francisella tularensis) [Search protein sequence]
MNRKVALEAVRVTELAALASWSQMGRGDKIAADQAAVDAMRKALNEVDID
GTVVIGEGELDEMLYIGEKVGAGGCEVDIALDPLEGTTITSKGGANALTV
LAMADKGGFLNAPDVYMQKIAVGGINAPKGIVDLDDSVTNNLKRIAEFKG
VHMSALVVCTMDRPRHEHIIKEARECGARVILINDGDVSGVIATATENSG
IDVYIGTGGAPEGVLAAAALKCLGGQMQARLIFNDEEEIKRAHRLGITDL
NKKYDIDDLASGDIVFAATGVTDGNMLQGVKRVNSTRRGSYAVTHSVVMR
STTKTVRHITAEHSFDFKEGIEKFMS
3D structure
PDB7txg New structures of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis provide a framework for a novel catalytic mechanism for the entire class.
ChainD
Resolution1.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.3.11: fructose-bisphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 D Y118 R165 R167 Y116 R163 R165
BS02 MN D E57 D84 L86 E57 D82 L84
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006071 glycerol metabolic process
GO:0006094 gluconeogenesis
GO:0030388 fructose 1,6-bisphosphate metabolic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7txg, PDBe:7txg, PDBj:7txg
PDBsum7txg
PubMed37352301
UniProtQ5NEJ8

[Back to BioLiP]