Structure of PDB 7txa Chain D

Receptor sequence
>7txaD (length=324) Species: 263 (Francisella tularensis) [Search protein sequence]
VALEAVRVTELAALASWSQMGRGDKIAADQAAVDAMRKALNEVDIDGTVV
IGEGELDEAPMLYIGEKVGAGGCEVDIALDPLEGTTITSKGGANALTVLA
MADKGGFLNAPDVYMQKIAVGGINAPKGIVDLDDSVTNNLKRIAEFKGVH
MSALVVCTMDRPRHEHIIKEARECGARVILINDGDVSGVIATATENSGID
VYIGTGGAPEGVLAAAALKCLGGQMQARLIFNDEEEIKRAHRLGITDLNK
KYDIDDLASGDIVFAATGVTDGNMLQGVKRVNSTRRGSYAVTHSVVMRST
TKTVRHITAEHSFDFKEGIEKFMS
3D structure
PDB7txa New structures of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis provide a framework for a novel catalytic mechanism for the entire class.
ChainD
Resolution2.4 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.3.11: fructose-bisphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN D D84 L86 E87 D80 L82 E83
BS02 MN D D116 E214 D112 E210
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0006071 glycerol metabolic process
GO:0006094 gluconeogenesis
GO:0030388 fructose 1,6-bisphosphate metabolic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7txa, PDBe:7txa, PDBj:7txa
PDBsum7txa
PubMed37352301
UniProtQ5NEJ8

[Back to BioLiP]